产品货号：
Z33766
中文名称：
SIT/SIT1抗体
英文名称：
Anti-SIT/SIT1 Antibody (Clone#SIT-01)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIT/SIT1 Antibody (Clone#SIT-01) |
| 指标别名 | SIT1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB |
| 基因名称 | SIT1 |
| 克隆号 | SIT-01 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Bacterially produced recombinant intracellular fragment of human SIT.The antibody SIT-01 reacts with an intracellular epitope of SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs. |
| 计算分子量 | 21kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development.Binding to Grb2 plays a pivotal role in signal transduction.Hubener et al.(2001) determined that the SIT gene contains 5 exons and spans 1.8kb of genomic DNA.The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors. |
| Uniprot ID | Q9Y3P8 |
| 基因名全称 | Signaling threshold regulating transmembrane adapt |
| 蛋白名全称 | Signaling threshold-regulating transmembrane adapter 1 |
| 推荐稀释比 | Flow cytometry:1～5μg/mL,intracellular staining. Western blotting:1～2μg/mL,reducing conditions. |
相关搜索：SIT/SIT1抗体，SIT抗体，SIT1单抗，Anti-SIT/SIT1 Antibody (Clone#SIT-01)